Emerging recombinant noroviruses identified by clinical and waste water screening
نویسندگان
چکیده
منابع مشابه
Are Noroviruses Emerging?
(previously called " Norwalk-like viruses ") were discovered as the first viruses definitively associated with acute gastroenteritis. During the next 2 decades, researchers were unable to develop simple methods to detect these common viruses or to find the etiolog-ic agents of nonbacterial gastroenteritis outbreaks and hospitalizations. Indeed, of >2,500 foodborne outbreaks reported to the Cent...
متن کاملCharacterization of new recombinant noroviruses.
Noroviruses are important etiologic agents of acute gastroenteritis and show great genetic diversity. To characterize more fully previously detected strains that could not be assigned unequivocally to one particular genotype based on the RNA polymerase, we have sequenced a region in the capsid gene and, in some cases, in the junction between open reading frame 1 (ORF 1) and ORF 2. The results a...
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Human noroviruses in the family Caliciviridae are a major cause of epidemic gastroenteritis. They are responsible for at least 95% of viral outbreaks and over 50% of all outbreaks worldwide. Transmission of these highly infectious plus-stranded RNA viruses occurs primarily through contaminated food or water, but also through person-to-person contact and exposure to fomites. Norovirus infections...
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A quantitative on-bead screening of a combinatorial octapeptide library revealed catalysts with hydrolytic activity in water. Histidine is an essential amino acid but the catalytic activity as well as the substrate binding affinity is also dependent on the sequence of the octapeptide.
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BACKGROUND Fatty acid oxidation disorders (FAODs) include more than 15 distinct disorders with variable clinical manifestations. After the introduction of newborn screening using tandem mass spectrometry, early identification of FAODs became feasible. This study describes the clinical, biochemical and molecular characteristics of FAODs patients detected by newborn screening (NBS) compared with ...
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ژورنال
عنوان ژورنال: Emerging Microbes & Infections
سال: 2018
ISSN: 2222-1751
DOI: 10.1038/s41426-018-0047-8